Medicines to be Used in Infective Diarrhoea and Severe Diarrhea

The drugs in this aggregation are used for overcoming diarrhea due to infection. These bear furazolidone, sulfonamides, and antibiotics.
Furazolidone (Furoxone)
This drug has been found to be effective in controlling diarrhoea due to a large variety of micro-organisms. An foremost characteristic is that micro-organisms effect not progress resistance to this drug. It is a valuable agent in the treatment of gastro-enteritis and infections which are resistant to sulfadiazine, tetracycline or chloramphenicol. It is extremely available in combination with metronidazole - an antiamoebic drug. The general adult verbal dose is 100 mg, four times a day. Children hurting for 5 to 10 mg/kg body weight in 3 to 4 divided doses (Furoxone 25 mg/ml)
Adverse Effects: Adverse part of this narcotic are minimal. It may agency nausea, vomiting, headache, and in rare cases, susceptible reaction in the form of skin rashes.
Precautions
The drug should not be taken on an empty stomach.
If severe nausea or vomiting are experienced, doses should be reduced or drug withdrawn.
The drug should be stopped provided symptoms of averse reaction occur.
Neomycin, Colistin Sulfate (Walamycin)
Neomycin is an antibiotic found to be of special rate in the treatment of diarrhea in infants because of its district action. It is normally given in combination with other non-specific anti diarrhoea drugs.
Ampicillin (Ampicillin Campicillin)
Nowadays ampicillin is a drug of election in the treatment of bacillary dysentery
Norfloxacin (Norflox, Uroflox)
It is a fluoroquinolone which is efficacious against microbes causing diarrhea and urinary infection. Typical dose is 400 mg twice a day. Manufacturers forbid its adoption in children. Unfortunately a bulky symbol of preparations contain pediatric syrups/dispersable tablets which keep been used. This drug can produce cartilage damage. Adverse effects are nausea, vomiting, headache, dizziness, dry mouth, loss of sleep and convulsions. Its use should be restricted.
Drugs Used in Severe Diarrhea
In severe types of dirrhea and in diarrhoea associated with vomiting, immediate concern is necessary. Very the use of effectual drugs, fluid and electrolyte balance should be corrected to avoid dehydration. Dehydration is characterized by hot and dry skin over the abdomen, dry language and lips, sunken eyeballs, and shock. In such cases, fluids should be infused through an intravenous drip and anti-spasmodics and antibiotics should be given.
A number of drugs are available for the treatment and shown in table below:
Drugs Used in Irritable Bowel Syndrome
Irritable bowel syndrome (IRS) is a common functional disorder of intestines. A patient with IBS has complaints such as abdominal pain, constipation or diarrhea. Investigation divulge normal structures. Many patients are treated unnecessarily with antiamoebic and antibacterial drugs.
Treatment depends on the environment of complaints. Many patients come around with eating more fibres (Isabgol pod may be added). In others, fiber propertied diet increases gaseousness and bloating.
Two types of drugs are useful in this disorder:
Those who acquire loose stools can benefit from diphenoxylate or loperamide. Antidepressants
and diazepam also helps.
Those who have constipation have need drugs prize cisapride, mosapride and tegaserod. Tegaserod (TEGIBS 2 mg, 6 mg cap) is a new drug available in India. It is used in IBS when constipation is the leading complaint (spastic colon).

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